abstract：:The aim of our study was to assess the incidence course, influence on liver function, diagnostic methods, prophylaxis of, and cost treatment effectiveness of CMV infection among 123 consecutive liver transplant recipients. All patients received immunoglobulin and parenterall gancyclovir as prophylaxis. CMV IgM and IgG...

journal_title：Transplantation proceedings

authors： Oldakowska-Jedynak U,Niewczas M,Ziolkowski J,Mucha K,Foroncewicz B,Bartlomiejczyk I,Senatorski G,Wyzgal J,Krawczyk M,Zieniewicz K,Nyckowski P,Paczek L

更新日期：2003-09-01 00:00:00

abstract：:The so-called learning factor has been disregarded for many years in analyzing the causes of surgical complications and post-operative mortality; it is also the case for OLT. In our center until April 2003, 209 OLT were performed in 196 patients. We evaluated the impact of experience of the transplantation team on the...

journal_title：Transplantation proceedings

authors： Krawczyk M,Grzelak I,Zieniewicz K,Nyckowski P,Pawlak J,Michałowicz B,Patkowski W,Alsharabi A,Wróblewski T,Paluszkiewicz R,Małkowski P,Hevelke P,Pszenny C,Remiszewski P,Skwarek A,Smoter P,Grodzicki M,Kornasiewicz O,Kor

更新日期：2003-09-01 00:00:00

abstract：:Our previous study of a group of renal transplant recipients treated with CsA showed a significantly faster development of chronic graft failure among patients with gingival hyperplasia (GH) compared to unaffected patients. The aim of the present research was to establish the impact of CsA dose and blood levels on the...

journal_title：Transplantation proceedings

authors： Boratyńska M,Radwan-Oczko M,Falkiewicz K,Klinger M,Szyber P

更新日期：2003-09-01 00:00:00

abstract：:Our previous observations showed alterations of oral cavity status among hemodialyzed patients and kidney allograft recipients as well as differences in the prevalence and composition of microorganisms occurring in the mouths of patients. In the present work, we analysed the results of oral cavity examinations, the id...

journal_title：Transplantation proceedings

authors： Piekarczyk J,Fiedor P,Chomicz L,Szubinska D,Starościak B,Piekarczyk B,Zawadzki P,Zebrowska J,Dudziński T

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:The aim of this retrospective study was to assess the incidence of acute rejection episodes (AR), diabetes mellitus (DM), and serum creatinine (SCr) among renal transplant recipients treated with tacrolimus (Tac), steroids (S), and mycophenolate mofetil (MMF) or azathioprine (Aza). METHODS:Seventy-five rena...

journal_title：Transplantation proceedings

authors： Mucha K,Foroncewicz B,Paczek L,Pazik J,Lewandowska D,Krawczyk A,Pliszczynski J,Gradowska L,Durlik M,Walaszewski J,Nazarewski S,Szmidt J

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:With living donation, in addition to the medical risk, the financial risk for the donor is essential, especially in case of complications that potentially can led to disability and loss of work. We report the experiences of those who have donated a kidney in our transplant center. METHODS:We contacted 80 do...

journal_title：Transplantation proceedings

authors： Wolters HH,Heidenreich S,Senninger N

更新日期：2003-09-01 00:00:00

abstract：:Depletion of anti-alphaGal antibodies before and after transplantation with GAS 914, a polylysine containing alphaGal epitopes, together with immunosuppression, has been shown to prevent acute humoral xenograft rejection (AHXR) in hDAF pig-to-baboon xenotransplantation. This therapy was associated with low levels of s...

journal_title：Transplantation proceedings

authors： Doménech N,Diaz T,Moscoso I,Centeno A,Lopez-Pelaez E,Manez R

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction has been found in the peripheral circulation of patients with severe heart failure. However, whether the endothelial dysfunction improves after heart transplantation remains unknown. Our aim was to assess the forearm endothelium-dependent vasoreactivity one and six months after heart ...

journal_title：Transplantation proceedings

authors： Cuppoletti A,Sitges M,Pérez Villa F,Orús J,Magriñá J,Roig E

更新日期：2003-08-01 00:00:00

abstract：:The aim of this study was to evaluate cyclosporine (CyA) absorption profiles in heart transplantation to establish the most adequate monitoring strategy and determine the optimal therapeutic range for AUC(0-4) or C2 levels. A total of 22 full pharmacokinetic studies were performed at steady-state in 22 adult heart tra...

journal_title：Transplantation proceedings

authors： Arizón del Prado JM,Aumente Rubio MD,Cárdenas Aranzana M,López Malo de Molina MD,Segura Saint-Gerons J,López Granados A,Rodríguez Esteban E,Ruiz Ortiz M,Romo Peñas E,Muñoz Carvajal I,González Rodríguez JR,Segura Saint-Gerons C,Va

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVES:We describe our experience with infants suffering from interstitial pneumonia referred for lung transplantation. METHODS:From April 1998 to December 2000, three infants were admitted to our lung transplantation program: a 9-month-old girl (patient 1) suffering from surfactant protein C deficiency who had hi...

journal_title：Transplantation proceedings

authors： Moreno A,Maestre J,Balcells J,Marhuenda C,Cobos N,Roman A,Soler J,Montferrer N,Liñan S,Gartner S,Roqueta J,Majo J

更新日期：2003-08-01 00:00:00

abstract：:Campath-1H is being used as induction immunosuppression for intestinal/multivisceral transplantation. Patient and graft survival in this preliminary experience is similar to previous studies but there has been a significant decrease in the incidence and severity of acute rejections without increase of opportunistic in...

journal_title：Transplantation proceedings

authors： Tzakis AG,Tryphonopoulos P,Kato T,Nishida S,Levi DM,Nery JR,Madariaga J,De Faria W,Mittal N,Thompson JF,Ruiz P

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to analyze the incidence, clinical characteristics, treatment, and outcome of upper aerodigestive (UAD) and lung de novo tumors after ortothopic liver transplantation (OLT). PATIENTS AND METHODS:Between April 1986 and June 2002, we performed 851 OLT in 753 patients. We excluded...

journal_title：Transplantation proceedings

authors： Jiménez C,Marqués E,Loinaz C,Romano DR,Gómez R,Meneu JC,Hernández-Vallejo G,Alonso O,Abradelo M,Garcia I,Moreno E

更新日期：2003-08-01 00:00:00

abstract：AIM:Our goal was to retrospectively analyze graft loss and mortality risk factors using multi-centre data on liver retransplantation. MATERIAL AND METHODS:Between 1991-1995, 640 patients underwent 718 liver transplants in Barcelona. Mean age of the 74 patients receiving a second transplant was 47.6 years (range 19-65)...

journal_title：Transplantation proceedings

authors： Bilbao I,Figueras J,Grande L,Clèries M,Jaurrieta E,Visa J,Margarit C

更新日期：2003-08-01 00:00:00

abstract：:Liver transplantation for chronic HBV-induced cirrhosis is associated with a high rate of recurrence and poor long-term survival. Prolonged and combined prophylaxis with hepatitis B immunoglobulin (HBIg) and lamivudine has been demonstrated to prevent HBV recurrence, but its lifelong administration is highly expensive...

journal_title：Transplantation proceedings

authors： Albeniz Arbizu E,Barcena Marugan R,Oton Nieto E,Carrera Alonso E,Garcia Gonzalez M,Moreno Garcia J,de Vicente Lopez E,Nuño Vazquez-Garza J,Martin Davila P

更新日期：2003-08-01 00:00:00

abstract：UNLABELLED:Currently liver transplantation is the treatment of choice for early hepatocellular carcinoma and end-stage liver disease. We analyzed our experience to identify factors that could be used to select patients who will benefit from liver transplantation. PATIENTS AND METHODS:From April 1986 to December 2001, ...

journal_title：Transplantation proceedings

authors： Pérez Saborido B,Loinaz Segurola C,Gimeno Calvo A,Meneu Díaz JC,Abradelo de Usera M,Calvo Pulido J,Jiménez Romero C,Gómez Sanz R,García García I,Moreno González E

更新日期：2003-08-01 00:00:00

abstract：:Ischemic preconditioning renders the liver more tolerant to ischemia-reperfusion injury in warm and cold ischemia-reperfusion models. In general, the application of a 5 to 10-minute period of ischemia followed by 10 minutes of reperfusion confers early effective protection to the liver. Mechanisms responsible for this...

journal_title：Transplantation proceedings

authors： Peralta C,Serafin A,Fernández-Zabalegui L,Wu ZY,Roselló-Catafau J

更新日期：2003-08-01 00:00:00

abstract：:Serial Doppler sonographic impedance measurements represent the most common diagnostic method for noninvasive monitoring of kidney grafts. Severely elevated arterial impedance is almost always associated with graft dysfunction. However, we describe in the present work a renal transplant recipient with optimal graft fu...

journal_title：Transplantation proceedings

authors： Salgado O,García R,Henríquez C,Rosales B,Sulbarán P

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Hepatitis C has been associated with an increased incidence of diabetes mellitus (DM) following renal transplantation (RT). METHODS:Patients who underwent RT between 1985 and 2001 were excluded if they showed DM prior to RT, graft survival of less than 90 days, and unknown anti-HCV status (n=15). Two groups...

journal_title：Transplantation proceedings

authors： Gentil MA,López M,González-Roncero F,Rodríguez-Algarra G,Pereira P,López R,Martínez M,Toro J,Mateos J

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to assess a Simulect (basiliximab) regimen in routine clinical practice in the Spanish kidney transplantation units to evaluate efficacy and safety. METHODS:In this prospective, observational study, data on demographics, parameters of efficacy, and safety in patients who under ...

journal_title：Transplantation proceedings

authors： Rengel M,Fernández Rodriguez A,Gómez Huertas E,Plaza JJ,Ruiz San Millán JC,Oppenheimer F,Bustamante J,Checa D,Sanchez Plumed JA,García Pérez J,Sanz Guajardo A,Llorente S,Martin Govantes JA,Gentil MA,Gomez Ullate P,Sanchez G

更新日期：2003-08-01 00:00:00

abstract：:Cyclosporine elimination in a regimen including sirolimus has been shown to be a safe and effective approach to improve graft function. Nevertheless, it is still unknown whether the functional benefit of CyA withdrawal coincides with a subsequent reduction in histologic lesions of chronic damage or development of chro...

journal_title：Transplantation proceedings

authors： Ruiz JC,Campistol JM,Mota A,Prats D,Gutiérrez JA,Castro A,García J,Morales JM,Grynió JM,Gómez JM,Arias M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Catalonia and Spain have the highest rates of organ donation in the world. The National Transplant Organization studied the rates of potential and actual donors through the Quality Guarantee Program, but this research did not estimate potential tissue donation (PTD). The aim of this study was to define the t...

journal_title：Transplantation proceedings

authors： Pont T,Gràcia RM,Valdés C,Nieto C,Rodellar L,Arancibia I,Deulofeu Vilarnau R

更新日期：2003-08-01 00:00:00

abstract：:FK506 is an immunosuppressant for organ transplantation in the same clinical settings as cyclosporine (CsA). In the management of liver transplantation, FK506 has advantages over CsA, in terms of rejection and corticosteroid requirements. Recent clinical findings in liver transplant patients indicate that FK506, but n...

journal_title：Transplantation proceedings

authors： Mabuchi M,Kawamura I,Takeshita S,Fushimi M,Takakura S,Hirosumi J,Mutoh S

更新日期：2003-06-01 00:00:00

abstract：:Thymidine ((3)H-TdR) incorporation remains the most commonly used method to quantifying T-cell proliferation. This method, however, does not provide information about specific lymphocyte subpopulations responding to different stimuli. In our study, we modified previously described nonradioactive flow-cytometric T-cell...

journal_title：Transplantation proceedings

authors： Kalwak K,Turkiewicz D,Ussowicz M,Gorczyńska E,Toporski J,Ryczan R,Rybka B,Noworolska-Sauren D,Chybicka A

更新日期：2003-06-01 00:00:00

abstract：:Hemophagocytic syndrome (HPS) is a life-threatening hematological disorder in immunocompromised patients. Although the number of patients with HPS following liver transplantation is scarce the outcome is usually fatal. We report a patient who developed HPS following living-related liver transplantation (LRLT) and was ...

journal_title：Transplantation proceedings

authors： Karasu Z,Kilic M,Cagirgan S,Lebe E,Yilmaz F,Demirbas T,Tokat Y

更新日期：2003-06-01 00:00:00

abstract：:The aim of this study was to investigate the impact of acute exercise on portal blood flow in liver transplant recipients compared to healthy subjects since it is known that transplantation produces a denervated liver and intrahepatic vascular tube. Twelve liver transplantation recipients and 12 age-gender-matched sub...

journal_title：Transplantation proceedings

authors： Ersoz G,Ersoz S

更新日期：2003-06-01 00:00:00

abstract：:In a retrospective study we analyzed the incidence and characteristics of de novo tumors developing in renal transplant recipients treated in our center. The 5% incidence de novo tumors developing among patients treated with azathioprine and prednisolone (n = 241) was similar to the 5.4% incidence of de novo tumors de...

journal_title：Transplantation proceedings

authors： Langer RM,Járay J,Tóth A,Hídvégi M,Végsö G,Perner F

更新日期：2003-06-01 00:00:00

abstract：:To assess the time-dependent changes in renal function in relation to antioxidant and lipid-lowering effects of fluvastatin in hyperlipidemic renal transplant recipients, 20 patients were treated with fluvastatin 40 mg/d for 12 months, after failure of a dietary program. Plasma malondialdehyde (MDA) levels and lipid p...

journal_title：Transplantation proceedings

authors： Konstadinidou I,Boletis JN,Perrea D,Triantafyllou A,Filiopoulos V,Stamataki E,Kostakis A,Stathakis ChP

更新日期：2003-06-01 00:00:00

abstract：INTRODUCTION:The EuroTransplant "old to old" program establishes that patients older than 60 years can receive offers of organs from donors older than 60 years. The compromised function of these organs makes it a priority to preserve their initial kidney function. HYPOTHESIS:Calcineurin-sparing protocols using anti-IL...

journal_title：Transplantation proceedings

authors： Emparan C,Laukötter M,Wolters H,Dame C,Heidenreich S,Senninger N

更新日期：2003-06-01 00:00:00

abstract：:The aim of this study was to evaluate the safety of conversion to sirolimus (SRL) immunosuppression among 19 renal transplant recipients (KTX) with progressive chronic renal allograft dysfunction (CRAD). Conversion to SRL was performed with concomitant sharp withdrawal of the calcineurin inhibitor (CI). SRL was added ...

journal_title：Transplantation proceedings

authors： Citterlo F,Scatà MC,Violi P,Romagnoli J,Pozzetto U,Nanni G,Castagneto M

更新日期：2003-06-01 00:00:00

abstract：:While the outcome following organ transplantation in the United Kingdom has never been better, the waiting list has never been longer and the organ shortage is now the most pressing issue. UK Transplant has invested in four initiatives to promote donor and transplant numbers: coordinating the coordinators, establishin...

journal_title：Transplantation proceedings

authors： Rudge CJ

更新日期：2003-05-01 00:00:00

abstract：:Recent therapeutic strategies to combat organ allograft rejection have focused on T-cell signaling pathways and the molecules that comprise them. The macrolide antibiotic produced by the bacterium Streptomyces hygroscopicus, known as sirolimus or rapamycin, has shown great therapeutic potential in the transplant setti...

journal_title：Transplantation proceedings

authors： Kirken RA,Wang YL

更新日期：2003-05-01 00:00:00

abstract：:It is now common practice to measure immunosuppressive drugs in blood as a guide to therapy. The immunosuppressive drug sirolimus, recently approved for use following kidney transplantation, was developed in the context of this clinical approach. Throughout the early clinical studies, validated analytical techniques b...

journal_title：Transplantation proceedings

authors： Holt DW,Denny K,Lee TD,Johnston A

更新日期：2003-05-01 00:00:00

abstract：:We report 6-month results of renal allograft recipients enrolled in seven Australian centers as part of a worldwide, multicenter, randomized, open-label, concentration-controlled trial comparing standard tacrolimus (sTAC) with reduced tacrolimus (rTAC) both with sirolimus (SRL) and steroids. Patients were randomized 1...

journal_title：Transplantation proceedings

authors： Russ GR,Campbell S,Chadban S,Eris J,O'Connell P,Pussell B,Walker R,Australian Rapamune-Tacrolimus Study Group.

更新日期：2003-05-01 00:00:00

abstract：:This review focuses upon the sirolimus-based cyclosporine elimination studies and the light they shed on choice of the best long-term immunosuppressive strategy for managing the balance between prevention of loss of grafts from antigen specific immune responses or from chronic nephrotoxicity. The underlying strategy o...

journal_title：Transplantation proceedings

authors： Chapman JR

更新日期：2003-05-01 00:00:00

abstract：:Our two meta-analyses show that antilymphocyte antibody induction therapy extends allograft survival when compared to induction therapy with cyclosporine, azathioprine, and prednisone with the majority of the benefit seen during the first 2 years after transplant. The benefit of induction therapy with respect to allog...

journal_title：Transplantation proceedings

authors： Szczech LA,Feldman HI

更新日期：1999-05-01 00:00:00

abstract：:Advances in the surgical techniques, preservation solutions, and methods for predicting eventual long-term renal function from expanded donors will be critical in allowing precise selection criteria for kidneys for transplantation, resulting in the optimum use of a scarce and precious resource. Until other options suc...

journal_title：Transplantation proceedings

authors： Jordan ML,Shapiro R,Vivas CA,Scantlebury VP,Corry RJ,Randhawa P,Hakala TR,Starzl TE

更新日期：1999-02-01 00:00:00

abstract：:Clinical chronic rejection corresponds histologically to proliferative allograft vasculopathy. This disorder reflects the cumulative trauma to the allograft regardless of its origin. As a consequence of trauma, inflammation is generated, leading to endothelial and smooth muscle cell activation, smooth muscle replicati...

journal_title：Transplantation proceedings

authors： Häyry P

更新日期：1998-08-01 00:00:00

abstract：:The mechanism of the immunosuppressive effect of CyA and FK 506 can be monitored in vivo in humans. The picture emerging is of a close relationship between drug concentrations and CN inhibition. But many puzzles of the drugs remain. What is the role of CyA in the activation of transforming growth factor-beta (TGF-beta...

journal_title：Transplantation proceedings

authors： Halloran PF,Kung L,Noujaim J

更新日期：1998-08-01 00:00:00

abstract：:Successful pancreas transplantation with systemic drainage is followed by a normalization of carbohydrate and lipid metabolism with low levels of plasma cholesterol and triglycerides. HDL cholesterol concentration and CETP plasma levels were found to be increased and the composition of lipoproteins altered in that LDL...

journal_title：Transplantation proceedings

authors： Königsrainer A,Föger B,Steurer W,Lechleitner M,Spechtenhauser B,Riedmann B,Patsch JR,Margreiter R

更新日期：1998-03-01 00:00:00

abstract：:We have alluded to data showing that effective organisation has a well-documented effect on organ donation. We have also presented data demonstrating the positive effect of the Transplant Games on public opinion and through positive media influence, producing a very marked increase in organ donation. Attention has als...

journal_title：Transplantation proceedings

authors： Slapak M

更新日期：1997-11-01 00:00:00